Thank you!
Your email is being processed.
Mood support; Cognitive support; Liver support; Joint comfort
Adults seeking a single-ingredient option for methylation support and those with busy routines who prefer once-daily dosing.
Adults take 1 tablet daily between meals; do not chew or crush. If stomach sensitivity occurs, taking with a small snack may be more comfortable.
Non-GMO; Gluten Free; Soy Free; Vegetarian
SAM-e donates methyl groups for neurotransmitter and phospholipid synthesis and supports transsulfuration pathways involved in glutathione production and joint tissue metabolism.
Caution: May cause digestive upset; take on an empty stomach as directed but consider a small snack if sensitive. Avoid use with bipolar disorder or with antidepressant medications unless guided by a healthcare professional due to mood and neurotransmitter effects.
Label Warning: Consult prescribing physician before use if taking antidepressant medications. Avoid use if diagnosed with bipolar disorder or manic depression. Do not use if pregnant or nursing. May cause gastrointestinal discomfort in some people.
Who should be cautious: People with mood disorders, on antidepressants, or with a history of gastrointestinal sensitivity may need extra caution. Consult a healthcare provider before combining with medications that may interact.
Storage: Store in a cool, dry place.
Many users mention feeling more balanced and mentally clear after starting the supplement.
Customers like the smooth, coated tablets that are simple to take.
A few users reported discomfort that made continued use challenging.
This product is guaranteed authentic and backed by our easy returns & refunds policy. Details
Glucosamine and chondroitin may support joint health and flexibility, complementing SAM-e's potential benefits for joint comfort.
AI generated. Not medical advice.
Sorry, there was a problem adding this item to cart. Please refresh the page and try again.
At Doctor's Best, SAM-e is a trusted ally for mood, joint, and liver health. Our Adonat® Premium SAMe formula is carefully crafted to support cellular functions, aid in cognition, and fuel crucial methylation reactions, vital for overall well-being.
Doctor's Best utilizes only the highest quality SAM-e providing slow and targeted release for improved GI tolerance and absorption.
Our Double-Strength SAM-e 400 contains 400mg of active SAM-e in each tablet.
This ensures that you receive the most potent SAM-e product with the highest percentage of the active S,S form per serving.
Double Strength SAM-e is sealed in blister packs for freshness and stability.
Adult Use: Take 1 tablet daily between meals, or as recommended by a nutritionally-informed physician. Do not chew or crush tablet.
Microcrystalline cellulose, magnesium silicate, stearic acid, magnesium stearate (vegetable source), flake shellac dewaxed, magnesium hydroxide, glycerol, silica, arginine base, sodium alginate, calcium oxide.
Individuals using antidepressant medications should consult with their prescribing physician prior to using this product. Individuals diagnosed with bipolar disease or manic depression should avoid supplementing with SAM-e. Do not use if pregnant or nursing. May cause gastrointestinal discomfort in a small percentage of people.
Store in a cool, dry place.
While iHerb strives to ensure the accuracy of its product images and information, some manufacturing changes to packaging and/or ingredients may be pending update on our site. Although items may occasionally ship with alternate packaging, freshness is always guaranteed. We recommend that you read labels, warnings and directions of all products before use and not rely solely on the information provided by iHerb.
| Supplement facts | ||
| Serving Size: 1 Tablet | ||
| Servings Per Container: 60 | ||
| Amount per serving | % Daily Value | |
| SAM-e ( S-Adenosyl Methionine disulfate p-toluensulfonate)(Adonat®) | 400 mg | † |
| †Daily Value not established. | ||
