NaturesPlus, Hema-Plex® Iron, 60 Fast-Acting Capsules

What it's for

Red blood cell support; Energy metabolism; Nutritional iron support

Who it may fit

Adults with low dietary iron intake or those seeking daily support for red blood cell production.

Key actives per serving

• Iron (as ferrous fumarate, amino acid chelate): 85 mg (472% DV)
• Vitamin C (ascorbyl palmitate, ascorbic acid, magnesium ascorbate, potassium ascorbate, zinc ascorbate): 300 mg (333% DV)
• Folate (as calcium-L-5-methyltetrahydrofolate): 667 mcg DFE (400 mcg L-methylfolate) (167% DV)
• Vitamin B12 (as methylcobalamin): 500 mcg (20833% DV)
• Copper (as amino acid chelate): 2 mg (222% DV)

How to take

Take 2 capsules daily, preferably with food. Iron-containing supplements may be better tolerated when taken with a meal and away from high-calcium foods or supplements.

Diet / Allergen fit

Non-GMO; Vegan; Gluten-Free; Free from synthetic preservatives; Free from: milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, soy, sesame. Contains no common allergens listed.

Iron (as ferrous fumarate, amino acid chelate)

Iron is a key component of hemoglobin and enzymes, helping transport oxygen and support energy production in cells.

Caution: High doses may cause gastrointestinal discomfort or constipation; take only as directed to avoid excess iron accumulation.

Vitamin C (ascorbyl palmitate, ascorbic acid, magnesium ascorbate, potassium ascorbate, zinc ascorbate)

Vitamin C enhances non-heme iron absorption in the gut and acts as an antioxidant to protect cells from oxidative stress.

Caution: May cause mild stomach upset in some people; consider taking with food if sensitive.

Folate (as calcium-L-5-methyltetrahydrofolate)

L-methylfolate is the active form used in red blood cell formation and methylation processes.

Caution: High intakes can mask low vitamin B12 status; consistent B12 intake is important.

Vitamin B12 (as methylcobalamin)

Vitamin B12 supports red blood cell formation and works in methylation pathways for energy metabolism.

Caution: Very high doses are generally well tolerated but may be unnecessary for those with adequate intake.

Copper (as amino acid chelate)

Copper is a cofactor for enzymes involved in iron transport and red blood cell maturation.

Caution: Excess copper can cause nausea; avoid combining with other high-copper supplements unless advised.

How they work together

Iron provides the core mineral for oxygen transport, while vitamin C increases iron absorption. Folate and vitamin B12 support red blood cell production and maturation, and copper aids iron mobilization and utilization for healthy blood formation.

Label Warning: Accidental overdose of iron-containing products can be fatal for children under 6. Keep out of reach of children. In case of overdose, contact a physician or poison control center immediately.

Who should be cautious: People taking thyroid medications, certain antibiotics, or levodopa should separate dosing from iron by at least 2 hours, as iron may reduce absorption. Those with hemochromatosis, other iron-loading conditions, or a history of stomach ulcers should discuss use with a healthcare provider. Pregnant or nursing individuals, and those with chronic health conditions, may want to consult a healthcare provider before use. If combining with medications that may interact with iron, it is recommended to consult a healthcare provider first.

Storage: Keep tightly closed in a cool, dry place.

Gentle on the stomach

Many reviewers mention fewer digestive issues and less constipation compared to other iron supplements.

Noticeable energy support

Users often report feeling more energetic after consistent use, and some note improved iron markers.

Possible taste or nausea

A few users mention an unpleasant taste or mild nausea; some also find the capsules large.